Either you have JavaScript disabled or your browser does not support Javascript . To work properly, this page requires JavaScript to be enabled.
How to enable JavaScript in your browser?

MTX 652

Next Previous
Drug Profile

MTX 652

Alternative Names: MTX-652

Latest Information Update: 28 Jun 2025

Price :
$50 *
Note:
  • Adis is an information provider. We do not sell or distribute actual drugs.
  • Final gross price and currency may vary according to local VAT and billing address.
  • Your purchase entitles you to full access to the information contained in our drug profile at the time of purchase.
  • A link to download a PDF version of the drug profile will be included in your email receipt.

At a glance

  • Originator MISSION Therapeutics
  • Class Antifibrotics; Heart failure therapies; Small molecules; Urologics
  • Mechanism of Action Usp30 protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase I Heart failure; Idiopathic pulmonary fibrosis; Muscular dystrophies; Renal failure
  • No development reported Acute kidney injury

Most Recent Events

  • 28 Jun 2025 No recent reports of development identified for phase-I development in Acute kidney injury(In volunteers) in United Kingdom (PO)
  • 16 Nov 2024 Pharmacodynamics data from preclinical studies in Heart failure presented at the American Heart Association Scientific Sessions 2024 (AHA-2024)
  • 14 Dec 2023 US FDA approves IND application for a phase II trial of MTX 652 in Acute kidney injury

You need to be a logged in or subscribed to view this content

Request demo (opens in a new window)
If your organization or you do not have a subscription, try one of the following: If your organization has a subscription, there are several access options, even while working remotely:
  • Working within your organization’s network
  • with username/password or try to via your institution
  • Persisted access using your organization’s identifier stored in your user browser for 90 days
Back to top