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Bis 5

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Drug Profile

Bis 5

Alternative Names: BIS-5; LNL-005

Latest Information Update: 13 Jul 2023

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At a glance

  • Originator L and L Biopharma
  • Class Antineoplastics; Bispecific antibodies; Immunotherapies
  • Mechanism of Action Antibody-dependent cell cytotoxicity; HAVCR2 protein inhibitors; Programmed cell death 1 receptor antagonists; T lymphocyte stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Colorectal cancer; Non-small cell lung cancer; Solid tumours

Most Recent Events

  • 12 Jul 2023 Phase-I clinical trials in Colorectal cancer in China (Parenteral) (L and L Biopharma pipeline, July 2023)
  • 12 Jul 2023 Phase-I clinical trials in Colorectal cancer in USA (Parenteral) (L and L Biopharma pipeline, July 2023)
  • 30 Jun 2022 Phase-I clinical trials in Non-small cell lung cancer (Second-line therapy or greater) (Parenteral) (L and L Biopharma pipeline,

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