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BN 104

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Drug Profile

BN 104

Alternative Names: BN-104; BNM-1192; S-243249

Latest Information Update: 06 Aug 2025

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At a glance

  • Originator BioNova Pharmaceuticals
  • Class Antineoplastics; Small molecules
  • Mechanism of Action Menin inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Acute myeloid leukaemia
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Acute myeloid leukaemia
  • Phase I/II Precursor B-cell lymphoblastic leukaemia-lymphoma

Most Recent Events

  • 01 Aug 2025 Phase-II clinical trials in Acute myeloid leukaemia (In adolescents, In adults, In the elderly) in China (PO) (NCT07101497)
  • 13 Feb 2025 BioNova Pharmaceuticals completes a phase I pharmacokinetic trial in healthy volunteers in China (PO, Tablet) (NCT06724549)
  • 12 Jan 2025 BioNova Pharmaceuticals initiates a phase I pharmacokinetic trial in healthy volunteers in China (PO, Tablet) (NCT06724549)

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