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JS 105

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Drug Profile

JS 105

Alternative Names: JS-105; RP-903

Latest Information Update: 18 Mar 2024

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At a glance

  • Originator Risen Pharma
  • Developer Risen Pharma; Shanghai Junshi Biosciences
  • Class Antineoplastics; Small molecules
  • Mechanism of Action Phosphatidylinositol 3 kinase alpha inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I/II Solid tumours
  • Phase I Breast cancer

Most Recent Events

  • 17 Jan 2024 Risen Pharma plans a phase Ib/II trial for Solid tumours (Combination therapy, Late-stage disease, Metastatic disease, Second-line therapy or greater) in China (PO) in February 2024 (NCT06208410)
  • 11 Jan 2024 Phase-I/II clinical trials in Solid tumours (Combination therapy, Late-stage disease, Metastatic disease, Second-line therapy or greater) in China (PO) (NCT06208410)
  • 30 Mar 2023 Phase-I clinical trials in Breast cancer in China (PO) (Shanghai Junshi Biosciences pipeline, April 2023)

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