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SIM 0272

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Drug Profile

SIM 0272

Alternative Names: SCR-6277; SCR-6920; SIM-0272

Latest Information Update: 16 Jul 2026

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At a glance

  • Originator Simcere Pharmaceutical Group
  • Class Antineoplastics; Small molecules
  • Mechanism of Action PRMT5 protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Non-Hodgkin's lymphoma; Solid tumours

Most Recent Events

  • 17 Apr 2026 SIM 0272 is still in phase I development in phase-I development in Non-Hodgkin's-lymphoma (Late-stage disease, Metastatic disease, Second-line therapy or greater) in China (PO, Capsule) (NCT05528055)
  • 17 Apr 2026 SIM 0272 is still in phase I development in Solid-tumours(Late-stage disease, Metastatic disease, Second-line therapy or greater) in China (PO, Capsule) (NCT05528055)
  • 17 Apr 2026 Pharmacodynamics data from preclinical data in Solid tumours presented at the 117th Annual Meeting of the American Association for Cancer Research (AACR-2026)

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