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AMG 794

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Drug Profile

AMG 794

Alternative Names: AMG-794

Latest Information Update: 26 Jul 2024

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At a glance

  • Originator Amgen
  • Class Antineoplastics; Bispecific antibodies; Immunoglobulin fragments; Immunotherapies; Recombinant fusion proteins
  • Mechanism of Action Immunologic cytotoxicity; T lymphocyte stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Non-small cell lung cancer; Ovarian cancer; Solid tumours

Most Recent Events

  • 08 Jul 2024 Amgen terminates a phase I trial in Solid tumours, Ovarian cancer, Non-small cell lung cancer (Inoperable/Unresectable, Late-stage disease, Metastatic disease, Second-line therapy or greater) in USA, Switzerland, Australia (IV), due to business decision to discontinue development of AMG 794 (NCT05317078)
  • 28 Feb 2023 Phase-I clinical trials in Non-small cell lung cancer (Inoperable/Unresectable, Late-stage disease, Metastatic disease, Second-line therapy or greater) in Switzerland, Australia (IV) (NCT05317078)
  • 28 Feb 2023 Phase-I clinical trials in Ovarian cancer (Inoperable/Unresectable, Metastatic disease, Late-stage disease, Second-line therapy or greater) in Australia, Switzerland (IV) (NCT05317078)

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