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Drug Profile


Alternative Names: SQZ-eAPC-HPV

Latest Information Update: 04 Mar 2024

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At a glance

  • Originator SQZ Biotech
  • Class Antineoplastics; Cancer vaccines; Cell therapies; Immunotherapies
  • Mechanism of Action Cell replacements; Immunologic cytotoxicity; T lymphocyte stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Phase I/II Solid tumours

Most Recent Events

  • 27 Nov 2023 SQZ Biotech terminates the phase-I/II COMMANDER-001 trial in Solid tumours (Late-stage disease, Metastatic disease, Monotherapy, Combination therapy, Second-line therapy or greater) in USA due to the corporate decision made by the company (NCT05357898)
  • 03 Nov 2023 Efficacy and adverse events data from the phase I/II COMMANDER-001 trial in Solid tumours released by SQZ Biotech
  • 06 Dec 2022 SQZ eAPC HPV receives Fast Track designation for Solid tumours [Parenteral] (Late-stage disease, Metastatic disease, Monotherapy, Second-line therapy or greater, Treatment-experienced) in USA
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