AK 129
Alternative Names: AK-129Latest Information Update: 22 Jun 2025
At a glance
- Originator Akeso Biopharma
- Class Antineoplastics; Bispecific antibodies; Immunotherapies
- Mechanism of Action Antibody-dependent cell cytotoxicity; CD223 antigen inhibitors; Programmed cell death-1 ligand-1 inhibitors; T lymphocyte stimulants
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Phase I/II Hodgkin's disease; Solid tumours
Most Recent Events
- 22 Jun 2025 700382230 CTP Push - KDM, DT, HE
- 21 May 2025 Phase-I/II clinical trials in Solid tumours (Combination therapy, Metastatic disease, Late-stage disease, Second-line therapy or greater, Recurrent) in China (IV) (NCT06943820)
- 24 Apr 2025 Akeso Biopharma plans a phase Ib/II trial for Solid tumours (Combination therapy, Late-stage disease, Metastatic disease) in China (IV, Infusion) in May 2025 (NCT06943820)