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PEBL-Chimeric antigen receptor T cell therapy - MediSix Therapeutics/Twist Bioscience

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Drug Profile

PEBL-Chimeric antigen receptor T cell therapy - MediSix Therapeutics/Twist Bioscience

Alternative Names: Research programme: Chimeric antigen receptor T cell therapies - MediSix Therapeutics/Twist Bioscience

Latest Information Update: 24 Feb 2025

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At a glance

  • Originator MediSix Therapeutics; Twist Bioscience
  • Class Antibodies; CAR-T cell therapies; Gene therapies; Immunotherapies
  • Mechanism of Action Immunologic cytotoxicity; T lymphocyte replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Phase I/II Precursor B-cell lymphoblastic leukaemia-lymphoma
  • Research Autoimmune disorders; Cancer

Most Recent Events

  • 07 Dec 2024 Efficacy and adverse event data from a phase I/II trial in Precursor B-cell lymphoblastic leukaemia-lymphoma presented at the 66th American Society of Hematology Annual Meeting and Exposition (ASH-Hem-2024)
  • 21 Apr 2024 Phase-I/II clinical trials in Precursor B-cell lymphoblastic leukaemia-lymphoma (In infants, In children, In adults, Second-line therapy or greater) in Italy (IV) (NCT06064903)
  • 20 Mar 2023 MediSix Therapeutics pipeline, March 2023 - Dev line and intro added

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