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ISB 2001

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Drug Profile

ISB 2001

Alternative Names: ABBV-2001; ISB-2001; TREAT™ trispecific antibody - Ichnos Sciences

Latest Information Update: 22 Sep 2026

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At a glance

  • Originator Ichnos Sciences
  • Class Antineoplastics; Immunoglobulin fragments; Immunotherapies; Recombinant fusion proteins; Trispecific antibodies
  • Mechanism of Action Immunologic cytotoxicity; T lymphocyte stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Multiple myeloma
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Multiple myeloma

Most Recent Events

  • 22 Sep 2026 ISB 2001 is still in phase-I trials for Multiple-myeloma (Second-line therapy or greater) in Australia (NCT05862012)
  • 28 Aug 2026 No recent reports of development identified for phase-I development in Multiple-myeloma(Second-line therapy or greater) in Australia (Parenteral, Injection)
  • 28 Dec 2025 No recent reports of development identified for preclinical development in Haematological-malignancies in USA (Parenteral)

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