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ISB 2001

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Drug Profile

ISB 2001

Alternative Names: ABBV-2001; ISB-2001; TREAT™ trispecific antibody - Ichnos Sciences

Latest Information Update: 28 Dec 2025

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At a glance

  • Originator Ichnos Sciences
  • Class Antineoplastics; Immunoglobulin fragments; Immunotherapies; Recombinant fusion proteins; Trispecific antibodies
  • Mechanism of Action Immunologic cytotoxicity; T lymphocyte stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Multiple myeloma
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Multiple myeloma

Most Recent Events

  • 28 Dec 2025 No recent reports of development identified for preclinical development in Haematological-malignancies in USA (Parenteral)
  • 10 Jul 2025 ISB 2001 licensed to Abbvie in North America, Europe, Japan, Hong Kong, Macau, Taiwan and China
  • 12 Jun 2025 Updated efficacy and adverse event data from phase I trial in Multiple myeloma presented at the 30th Congress of the European Haematology Association 2025 (EHA-2025)

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