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ALM 223

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Drug Profile

ALM 223

Alternative Names: ALM-223; IL-2muFc - Almirall S.A; SIM 0278

Latest Information Update: 22 Sep 2025

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At a glance

  • Originator Simcere Pharmaceutical Group
  • Developer Almirall S.A.; Simcere Pharmaceutical Group
  • Class Antidementias; Immunoglobulin Fc fragments; Immunotherapies; Interleukins; Recombinant fusion proteins
  • Mechanism of Action Interleukin 2 replacements; Natural killer cell stimulants; Regulatory T-lymphocyte stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Alzheimer's disease; Autoimmune disorders; Systemic lupus erythematosus

Most Recent Events

  • 16 Sep 2025 Jiangsu Simcere Pharmaceutical plans a phase II trial for Atopic dermatitis in China (Parenteral, Injection) in October 2025 (NCT07175233)
  • 21 Dec 2023 Phase-I clinical trials in Autoimmune disorders (unspecified route)
  • 09 Nov 2023 Almirall plans to initiate a phase I clinical trial for ALM 223 around the end of 2023

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