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ALM 223

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Drug Profile

ALM 223

Alternative Names: ALM-223; IL-2muFc - Almirall S.A; SIM 0278

Latest Information Update: 27 Feb 2026

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At a glance

  • Originator Simcere Pharmaceutical Group
  • Developer Almirall S.A.; Simcere Pharmaceutical Group
  • Class Anti-inflammatories; Antidementias; Immunoglobulin Fc fragments; Immunotherapies; Interleukins; Recombinant fusion proteins; Skin disorder therapies
  • Mechanism of Action Interleukin 2 replacements; Natural killer cell stimulants; Regulatory T-lymphocyte stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Alopecia areata; Atopic dermatitis
  • Phase I Autoimmune disorders
  • Preclinical Alzheimer's disease

Most Recent Events

  • 27 Feb 2026 Phase-II clinical trials in Alopecia areata (unspecified route) (Almirall pipeline, February 2026)
  • 06 Feb 2026 Simcere-Pharmaceutical-Group plans a phase IIa trial for Lupus nephritis in China (Injection) in March 2026 (NCT07393451)
  • 10 Nov 2025 Phase-II clinical trials in Atopic dermatitis in China (SC) (NCT07175233)

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