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DNTH 103

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Drug Profile

DNTH 103

Alternative Names: DNTH-103

Latest Information Update: 13 May 2025

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At a glance

  • Originator Dianthus Therapeutics
  • Class Antianaemics; Monoclonal antibodies
  • Mechanism of Action Complement C1s inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Chronic inflammatory demyelinating polyradiculoneuropathy
  • Phase II Multifocal motor neuropathy; Myasthenia gravis
  • Phase I Autoimmune disorders

Most Recent Events

  • 05 May 2025 Dianthus plans a phase II trial in Myasthenia gravis in Sweden, Netherlands, Argentina, Norway, Macedonia, Czech Republic, Denmark, France, Israel, Italy, USA, Canada, Poland, Serbia (SC) (NCT06282159)
  • 11 Mar 2025 Dianthus plans to file BLA for DNTH 103 in Chronic inflammatory demyelinating polyradiculoneuropathy
  • 10 Feb 2025 Dianthus Therapeutics has four pending PCT applications and four pending non-provisional applications for DNTH 103 in USA

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