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BR 105

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Drug Profile

BR 105

Alternative Names: BR-105

Latest Information Update: 26 Oct 2023

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At a glance

  • Originator Zhejiang Hisun Pharmaceutical
  • Class Antineoplastics; Immunotherapies; Monoclonal antibodies
  • Mechanism of Action Phagocyte stimulants; SIRPA protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Cancer

Most Recent Events

  • 24 Oct 2023 Phase-I clinical trials in Cancer (Late-stage disease, Second-line therapy or greater) in China (IV) before October 2023 (NCT05351697) (CTR20220467)
  • 24 Oct 2023 US FDA approves CTA application for BR 105 in Solid tumours
  • 24 Oct 2023 Preliminary adverse events data from a phase I trial in Solid tumours released by ZheJiang Hisun BioRay Bio-Pharmaceutical

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