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LB 1410

Drug Profile

LB 1410

Alternative Names: LB-1410

Latest Information Update: 28 Sep 2025

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At a glance

  • Originator L and L Biopharma
  • Class Antineoplastics; Bispecific antibodies; Immunotherapies
  • Mechanism of Action Antibody-dependent cell cytotoxicity; HAVCR2 protein inhibitors; Programmed cell death 1 receptor antagonists; T lymphocyte stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I/II Solid tumours
  • No development reported Lymphoma

Most Recent Events

  • 28 Sep 2025 No recent reports of development identified for phase-I development in Lymphoma(Late-stage disease, Metastatic disease, Second-line therapy or greater) in China (IV, Injection)
  • 17 Sep 2025 L & L Bio plans a phase II/III trial for Cervical cancer (Combination therapy, Recurrent, Metastatic disease, Late-stage disease) in China (IV) (NCT07177716)
  • 30 May 2025 Adverse events and efficacy data from phase I trial in Solid tumours presented at the 61st Annual Meeting of the American Society of Clinical Oncology (ASCO-2025)

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