LB 1410
Alternative Names: LB-1410Latest Information Update: 28 Sep 2025
At a glance
- Originator L and L Biopharma
- Class Antineoplastics; Bispecific antibodies; Immunotherapies
- Mechanism of Action Antibody-dependent cell cytotoxicity; HAVCR2 protein inhibitors; Programmed cell death 1 receptor antagonists; T lymphocyte stimulants
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Phase I/II Solid tumours
- No development reported Lymphoma
Most Recent Events
- 28 Sep 2025 No recent reports of development identified for phase-I development in Lymphoma(Late-stage disease, Metastatic disease, Second-line therapy or greater) in China (IV, Injection)
- 17 Sep 2025 L & L Bio plans a phase II/III trial for Cervical cancer (Combination therapy, Recurrent, Metastatic disease, Late-stage disease) in China (IV) (NCT07177716)
- 30 May 2025 Adverse events and efficacy data from phase I trial in Solid tumours presented at the 61st Annual Meeting of the American Society of Clinical Oncology (ASCO-2025)