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LPH 5

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Drug Profile

LPH 5

Alternative Names: LPH-5

Latest Information Update: 16 Mar 2026

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At a glance

  • Originator Lophora
  • Developer Atai Beckley; Lophora
  • Class Antidepressants; Phenethylamines; Piperidines; Small molecules
  • Mechanism of Action Serotonin 5-HT2A receptor agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Treatment-resistant depressive disorder

Most Recent Events

  • 16 Mar 2026 Phase-I clinical trials in Treatment resistant depressive disorder (In volunteers) (unspecified route)
  • 05 Nov 2025 ATAI Life Sciences has merged with Beckley Psytech to form Atai Beckley
  • 09 Dec 2024 Lophora plans phase I pharmacokinetics trial in healthy volunteers in April 2025 (NCT06722820)

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