Either you have JavaScript disabled or your browser does not support Javascript . To work properly, this page requires JavaScript to be enabled.
How to enable JavaScript in your browser?

UP 284

Next Previous
Drug Profile

UP 284

Alternative Names: UP-284

Latest Information Update: 24 Jun 2025

Price :
$50 *
Note:
  • Adis is an information provider. We do not sell or distribute actual drugs.
  • Final gross price and currency may vary according to local VAT and billing address.
  • Your purchase entitles you to full access to the information contained in our drug profile at the time of purchase.
  • A link to download a PDF version of the drug profile will be included in your email receipt.

At a glance

  • Originator Up Therapeutics
  • Developer Johns Hopkins University; Tuskegee University; Up Therapeutics
  • Class Antineoplastics; Small molecules
  • Mechanism of Action ADRM1 protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Glioblastoma; Ovarian cancer; Prostate cancer; Solid tumours; Triple negative breast cancer
  • Discontinued Multiple myeloma

Most Recent Events

  • 25 Apr 2025 Pharmacodynamics data from preclinical trials in Triple-negative breast cancer presented at the 116th Annual Meeting of the American Association for Cancer Research (AACR-2025)
  • 13 Sep 2023 Discontinued - Preclinical for Multiple myeloma in USA (unspecified route) (UP Therapeutics pipeline, September 2023)
  • 05 Sep 2023 Preclinical trials in Prostate cancer in USA, prior to September 2023 (unspecified route) (Up therapeutics pipeline, September 2023)

You need to be a logged in or subscribed to view this content

Request demo (opens in a new window)
If your organization or you do not have a subscription, try one of the following: If your organization has a subscription, there are several access options, even while working remotely:
  • Working within your organization’s network
  • with username/password or try to via your institution
  • Persisted access using your organization’s identifier stored in your user browser for 90 days
Back to top