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BMF 500

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Drug Profile

BMF 500

Alternative Names: BMF-500

Latest Information Update: 19 Jun 2025

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At a glance

  • Originator Biomea Fusion
  • Class Antineoplastics; Small molecules
  • Mechanism of Action Fms-like tyrosine kinase 3 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase I Acute biphenotypic leukaemia; Acute myeloid leukaemia; Precursor cell lymphoblastic leukaemia-lymphoma

Most Recent Events

  • 13 Jun 2025 Updated pharmacokinetics, pharmacodynamics, efficacy and adverse events data from a phase I COVALENT-103 trial in Acute myeloid leukaemia released by Biomea Fusion
  • 14 May 2025 Pharmacokinetics, pharmacodynamics, efficacy and adverse events data from a phase I trial in Acute myeloid leukaemia released by Biomea Fusion
  • 09 Dec 2024 Pharmacokinetics, pharmacodynamics, efficacy and adverse events data from a phase I trial in Acute myeloid leukaemia released by Biomea Fusion

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