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NBL 028

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Drug Profile

NBL 028

Alternative Names: anti-CLDN6-CD137 BsAb; NBL-028

Latest Information Update: 01 Feb 2024

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At a glance

  • Originator NovaRock Biotherapeutics
  • Class Antineoplastics; Bispecific antibodies; Immunotherapies
  • Mechanism of Action Antibody-dependent cell cytotoxicity; T lymphocyte stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Solid tumours

Most Recent Events

  • 31 Jan 2024 NovaRock Biotherapeutics plans a phase I trial for Solid tumours (Late-stage disease, Second-line therapy or greater) in China (IV, Infusion) in January 2024 (NCT06223256)
  • 08 Apr 2022 Preclinical trials in Solid tumours in USA (Parenteral) before April 2022
  • 08 Apr 2022 Pharmacodynamics data from a preclinical trial in solid tumours presented at the 113th Annual Meeting of the American Association for Cancer Research (AACR-2022)

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