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BRG 399

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Drug Profile

BRG 399

Alternative Names: BRG-399

Latest Information Update: 28 May 2026

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At a glance

  • Originator Berg Pharma
  • Developer BPG Bio
  • Class Anti-inflammatories; Antineoplastics; Cardiovascular therapies; Small molecules
  • Mechanism of Action Mitosis inhibitors; Tubulin polymerisation promoters; Ubiquitin protein ligase modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Cardiovascular disorders; Haematological malignancies
  • No development reported Solid tumours

Most Recent Events

  • 28 May 2026 No recent reports of development identified for preclinical development in Solid-tumours in USA (PO)
  • 06 Aug 2024 Preclinical trials in Cardiovascular disorders (Prevention) in USA (unspecified route) prior to August 2024 (BPG bio Pipeline, August 2024)
  • 06 Aug 2024 The US FDA approves IND application for BRG 399 in Solid tumours and Haematological malignancies prior to August 2024 (BPG bio Pipeline, August 2024)

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