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GC 503

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Drug Profile

GC 503

Alternative Names: Anti-mesothelin CAR-T cell therapy - Gracell Biotechnologies; GC-503

Latest Information Update: 26 Feb 2024

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At a glance

  • Originator Gracell Biotechnology
  • Class Antineoplastics; CAR-T cell therapies; Gene therapies; Immunotherapies
  • Mechanism of Action Immunologic cytotoxicity; T lymphocyte replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Phase I Solid tumours

Most Recent Events

  • 22 Feb 2024 Gracell Biotechnology has been acquired by AstraZeneca
  • 14 Nov 2022 Phase-I clinical trials in Solid tumours in China (IV), prior to November 2022
  • 30 May 2022 Gracell Biotechnology plans a phase-0 trial for Solid tumours (Late-stage disease, Second-line therapy or greater, Metastatic disease, ) in China (ChiCTR2200055490)

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