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HF 158K1

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Drug Profile

HF 158K1

Alternative Names: HF-158K1; HFK-1

Latest Information Update: 03 Sep 2025

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At a glance

  • Originator HighField Biopharmaceuticals
  • Class Anthracyclines; Antibodies; Antineoplastics; Cytostatic antibiotics; Doxorubicins; Drug conjugates; Fab fragments; Immunoconjugates
  • Mechanism of Action DNA intercalators; Type II DNA topoisomerase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Phase I Solid tumours

Most Recent Events

  • 30 May 2025 Pharmacokinetics data from a phase I trial in Solid tumour presented at the 61st Annual Meeting of the American Society of Clinical Oncology (ASCO-2025)
  • 21 Apr 2025 HighField Biopharmaceuticals files an IND application with the NMPA in China for Solid tumours
  • 21 Apr 2025 HighField Biopharmaceuticals plans a phase I trial in Solid tumours (Monotherapy, Combination therapy, Second-line therapy or greater) in China

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