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HF 158K1

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Drug Profile

HF 158K1

Alternative Names: HF-158K1; HFK-1

Latest Information Update: 15 Jul 2024

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At a glance

  • Originator HighField Biopharmaceuticals
  • Class Amines; Anthracyclines; Antibodies; Antineoplastics; Cytostatic antibiotics; Doxorubicins; Drug conjugates; Fab fragments; Hexanoic acids; Hydrazines; Immunoconjugates; Maleimides; Naphthacenes; Pyrroles; Small molecules
  • Mechanism of Action DNA intercalators; Type II DNA topoisomerase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Phase I Solid tumours

Most Recent Events

  • 15 Jul 2024 3862282 - Moa Added, Intro updated, Chem related DC and chemical structure need to add, thes req sent for - small molecules, doxorubicin, Fab fragment, anthracycline, Amines, Hexanoic-acids, Hydrazines, Maleimides, Naphthacenes, Pyrroles, NME may be need to change to NO, as active moiety is DOX, chemical formula number added
  • 28 May 2024 Pharmacodynamics data from a preclinical studies in Solid tumors released by HighField Biopharmaceuticals
  • 12 Dec 2023 Phase-I clinical trials in Solid tumours in USA (IV) (NCT05861895)

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