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C CAR 031

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Drug Profile

C CAR 031

Alternative Names: Anti-GPC3 CAR-T cell therapy - Astrazeneca; AZD-7003; C-CAR031

Latest Information Update: 11 Dec 2023

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At a glance

  • Originator AstraZeneca
  • Class Antineoplastics; CAR-T cell therapies; Gene therapies; Immunotherapies
  • Mechanism of Action Immunologic cytotoxicity; T lymphocyte replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Phase I Liver cancer

Most Recent Events

  • 07 Dec 2023 AbelZeta Pharma and AstraZeneca enter into an agreement to co-develop C CAR 031 .
  • 17 Apr 2023 Efficacy, adverse events and pharmacokinetics data from a phase I trial in Liver cancer released by Shanghai Cellular Biopharmaceutical
  • 14 Apr 2023 Pharmacodynamics data from phase I trial in Liver cancer presented at the 114th Annual Meeting of the American Association for Cancer Research (AACR-2023)
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