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LB 1908

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Drug Profile

LB 1908

Alternative Names: LB-1908; LCAR-C18S

Latest Information Update: 28 Oct 2024

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At a glance

  • Originator Legend Biotech USA
  • Class Antineoplastics; CAR-T cell therapies; Gene therapies; Immunotherapies
  • Mechanism of Action Immunologic cytotoxicity; T lymphocyte replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No
  • Available For Licensing Yes

Highest Development Phases

  • Phase I Gastric cancer; Oesophageal cancer; Pancreatic cancer
  • Preclinical Solid tumours

Most Recent Events

  • 28 Oct 2024 No recent reports of development identified for phase-I development in Solid-tumours(Late-stage disease, Metastatic disease, Second-line therapy or greater) in China (IV, Infusion)
  • 17 Jul 2023 Legend Biotech in collaboration with Shanghai East Hospital terminates a phase I trial in Solid tumours (Late-stage disease, Metastatic disease, Recurrent) in China (IV), due to collaborator's and sponsor's decision (NCT04467853)
  • 18 Apr 2023 Phase-I clinical trials in Gastric cancer (Late-stage disease, Second-line therapy or greater, Metastatic disease, Inoperable/Unresectable) in USA (IV) (NCT05539430)

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