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DNV 3

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Drug Profile

DNV 3

Alternative Names: DNV-3

Latest Information Update: 01 Apr 2026

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At a glance

  • Originator Zhejiang Shimai Pharmaceutical
  • Class Antineoplastics; Immunotherapies; Monoclonal antibodies
  • Mechanism of Action Antibody-dependent cell cytotoxicity; CD223 antigen inhibitors; T lymphocyte stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase II Lymphoma; Malignant melanoma; Solid tumours
  • Discontinued Multiple sclerosis

Most Recent Events

  • 17 Oct 2025 Adverse event and efficacy data from a phase 0 trial in Malignant melanoma presented at the 50th European Society for Medical Oncology Congress (ESMO-2025)
  • 18 Sep 2025 DNV 3 is available for licensing as of 18 Sep 2025. https://www.centrymed.com/science-pip (Zhejiang Shimai Pharmaceutical pipeline, September 2025)
  • 18 Sep 2025 Discontinued - Phase-I for Multiple sclerosis in China (Parenteral) (Zhejiang Shimai Pharmaceutical pipeline, September 2025)

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