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Recombinant collagenase - Connext

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Drug Profile

Recombinant collagenase - Connext

Alternative Names: CNT-201; CNT-202

Latest Information Update: 15 May 2025

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At a glance

  • Originator Connext
  • Class Collagenases; Recombinant proteins; Skin disorder therapies
  • Mechanism of Action Collagenase replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes - Cellulite; Dupuytren's contracture; Peyronie's disease; Wounds

Highest Development Phases

  • Phase I/II Dupuytren's contracture
  • Preclinical Cellulite; Peyronie's disease; Wounds

Most Recent Events

  • 07 May 2025 Connext plans to file an IND application for phase II trial with the US FDA for Peyronie’s disease by the third quarter of 2025
  • 07 May 2025 Adverse events data from phase-I/II clinical trials in Dupuytren's contracture released by Connext
  • 07 May 2025 Connext plans a global phase III trial for Dupuytren's contracture (Parenteral) in 2027

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