Elisrasib - D3 Bio
Alternative Names: D3S-001Latest Information Update: 10 Feb 2026
At a glance
- Originator D3 Bio
- Class 2 ring heterocyclic compounds; Acetonitriles; Alcohols; Alkenes; Aniline compounds; Antineoplastics; Azabicyclo compounds; Benzoates; Bridged bicyclo compounds; Carbamates; Cyclohexanols; Cyclohexenes; Esters; Fluorinated hydrocarbons; Fluorobenzenes; Heterocyclic bicyclo compounds; Heterocyclic compounds with 4 or more rings; Ketones; Methyl ethers; Piperazines; Pyrans; Pyrimidines; Pyrrolidines; Small molecules; Toluenes; Xylenes
- Mechanism of Action KRAS protein inhibitors
-
Orphan Drug Status
Yes - Pancreatic cancer; Colorectal cancer
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Phase II Colorectal cancer; Non-small cell lung cancer; Pancreatic cancer
- Phase I/II Solid tumours
Most Recent Events
- 19 Jan 2026 D3 Bio plans a phase-II trial for Non-small cell lung cancer (Second-line therapy or greater; Combination therapy) in USA (Unspecified)
- 19 Jan 2026 US FDA approves IND application for Elisrasib in Non-small cell lung cancer
- 10 Dec 2025 D3 Bio plans phase-III trial for KRAS G12C-mutant cancer(Monotherapy, Combination Therapy)(Indication) in United States, China, and the European Union