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AMT 116 - Multitude Therapeutics

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Drug Profile

AMT 116 - Multitude Therapeutics

Alternative Names: AMT-116 - Multitude Therapeutics

Latest Information Update: 28 Aug 2026

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At a glance

  • Originator Multitude Therapeutics
  • Class Antineoplastics; Drug conjugates; Immunoconjugates; Monoclonal antibodies
  • Mechanism of Action DNA topoisomerase I inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase I/II Non-small cell lung cancer; Solid tumours

Most Recent Events

  • 28 Aug 2026 No recent reports of development identified for phase-I development in Solid-tumours(Inoperable/Unresectable, Late-stage disease, Second-line therapy or greater) in USA (IV)
  • 28 Jul 2026 No recent reports of development identified for phase-I development in Solid-tumours(Inoperable/Unresectable, Late-stage disease, Second-line therapy or greater) in Australia (IV)
  • 22 Jul 2026 Multitude Therapeutics plans a phase II/III trial for Non-small cell lung cancer (Late-stage disease, Metastatic disease, Second-line therapy or greater) in Australia in August 2026 (IV, Infusion) (NCT07718737)

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