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Vorinostat - Unravel Biosciences

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Drug Profile

Vorinostat - Unravel Biosciences

Alternative Names: RVL-001

Latest Information Update: 20 Feb 2025

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At a glance

  • Originator Unravel Biosciences
  • Class Antineoplastics; Hydroxamic acids; Small molecules
  • Mechanism of Action Histone deacetylase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Rett syndrome
  • New Molecular Entity No

Highest Development Phases

  • Phase 0 Pitt-Hopkins syndrome; Rett syndrome

Most Recent Events

  • 20 Feb 2025 Phase-0 trials in Pitt-Hopkins syndrome in USA (unspecified route) prior to February 2025 (Unravel Biosciences Pipeline, February 2025)
  • 20 Feb 2025 Phase-0 trials in Rett syndrome in USA (unspecified route) prior to February 2025 (Unravel Biosciences Pipeline, February 2025)
  • 24 Oct 2024 Unravel Biosciences plans a proof-of-concept trial for Rett syndrome in Rett syndrome (RTT) and Pitt Hopkins syndrome (PTHS) in USA, in early 2025

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