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TGRX 326

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Drug Profile

TGRX 326

Alternative Names: TGRX-326

Latest Information Update: 24 Aug 2026

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At a glance

  • Originator Shenzhen TargetRx
  • Developer Shenzhen TargetRx; Sun Yat-Sen University Cancer Center
  • Class Antineoplastics; Small molecules
  • Mechanism of Action Anaplastic lymphoma kinase inhibitors; ROS1 protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Non-small cell lung cancer

Most Recent Events

  • 02 Jun 2026 Updated efficacy and adverse event data from a phase II trial in Non-small cell lung cancer presented at the 62nd Annual Meeting of the American Society of Clinical Oncology (ASCO-2026)
  • 02 Sep 2024 TGRX 326 licensed to Simcere Zaiming in Mainland China
  • 21 Jul 2024 Shenzhen TargetRx completes a phase I pharmacokinetics trial (In Volunteers) in China (PO) (NCT06438367)

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