Drug Profile

EVOLVE 101

Alternative Names: EV-101 - EvolveImmune Therapeutics; EVOLVE-101

Latest Information Update: 28 Aug 2026

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At a glance

Originator EvolveImmune Therapeutics
Class Antibodies; Antineoplastics; Immunotherapies; Recombinant proteins
Mechanism of Action Antibody-dependent cell cytotoxicity; Immunologic cytotoxicity; T lymphocyte stimulants

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

No development reported Acute myeloid leukaemia; Haematological malignancies

28 Aug 2026 No recent reports of development identified for research development in Acute-myeloid-leukaemia in USA (Parenteral)
28 Aug 2026 No recent reports of development identified for research development in Haematological-malignancies in USA (Parenteral)
24 Oct 2022 EvolveImmune Therapeutics plans a first-in-human clinical trial in Acute myeloid leukaemia and Haematological malignancies in 2024

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