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CX 2051

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Drug Profile

CX 2051

Alternative Names: CX-2051; EpCAM PROBODY® ADC

Latest Information Update: 21 Aug 2025

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At a glance

  • Originator ImmunoGen
  • Developer CytomX Therapeutics
  • Class Antibodies; Antineoplastics; Camptothecins; Drug conjugates; Immunoconjugates
  • Mechanism of Action DNA topoisomerase I inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase I Solid tumours

Most Recent Events

  • 13 Aug 2025 Adverse events data from a phase I trial in Solid tumours released by CytomX Therapeutics
  • 12 May 2025 Efficacy and adverse event data from phase I trial in Solid tumours released by CytomX Therapeutics
  • 12 May 2025 CytomX Therapeutics plans a phase Ib trial for Solid tumors in 2026

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