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CTX 112

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Drug Profile

CTX 112

Alternative Names: CTX-112; CTX112TM

Latest Information Update: 12 Dec 2024

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At a glance

  • Originator CRISPR Therapeutics
  • Class Antineoplastics; CAR-T cell therapies; Gene therapies; Immunotherapies
  • Mechanism of Action Immunologic cytotoxicity; T lymphocyte replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Phase I/II Haematological malignancies; Systemic lupus erythematosus
  • Preclinical Solid tumours

Most Recent Events

  • 09 Dec 2024 CTX 112 receives Regenerative Medicine Advanced Therapy (RMAT) status for Follicular lymphoma (Second-line therapy or greater) in USA
  • 09 Dec 2024 CTX 112 receives Regenerative Medicine Advanced Therapy (RMAT) status for Marginal zone B-cell lymphoma (Second-line therapy or greater) in USA
  • 09 Dec 2024 Preliminary pharmacokinetics and adverse events data from a phase I/II trial in Haematological malignancies released by CRISPR Therapeutics

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