CTX 131
Alternative Names: CTX-131; CTX131TMLatest Information Update: 15 Dec 2025
At a glance
- Originator CRISPR Therapeutics
- Class Antineoplastics; CAR-T cell therapies; Gene therapies; Immunotherapies
- Mechanism of Action Immunologic cytotoxicity; T lymphocyte replacements
-
Orphan Drug Status
No
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity No
Highest Development Phases
- Phase I/II Haematological malignancies; Solid tumours
Most Recent Events
- 18 Sep 2025 CRISPR Therapeutics completes a phase I/II trial in Solid tumours (Second-line therapy or greater, Inoperable/Unresectable, Metastatic disease, In adults, In the elderly) in USA (IV) (NCT05795595)
- 13 Aug 2024 Phase-I/II clinical trials in Haematological malignancies (Second-line therapy or greater) in USA (IV) (NCT06492304)
- 09 Jul 2024 CRISPR Therapeutics plans a phase I/II trial for Haematological malignancies (Second-line therapy or greater) in the US (IV) in the first half of 2024 (NCT06492304)