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HDT 401

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Drug Profile

HDT 401

Alternative Names: HDT-401; Riboxxim

Latest Information Update: 14 Jul 2026

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At a glance

  • Originator HDT Bio
  • Class Antineoplastics; Immunotherapies; RNA
  • Mechanism of Action DDX58 protein stimulants; Toll-like receptor 3 agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Glioblastoma

Most Recent Events

  • 12 Jul 2026 HDT Bio plans to file CTA application to Health Canada for Glioblastoma
  • 12 Jul 2026 HDT Bio in collaboration with McGill University and The Neuro plans a phase I trial for Glioblastoma in Canada
  • 09 Jun 2026 HDT Bio collaborates with Providence Swedish Neuroscience Institute (PSNI) for the development of HDT 401 for Glioblastoma

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