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LGR5-targeted CAR-T cell therapy - Carina Biotech

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Drug Profile

LGR5-targeted CAR-T cell therapy - Carina Biotech

Alternative Names: LGR5 stem cell antigen - Carina Biotech

Latest Information Update: 28 Aug 2026

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At a glance

  • Originator Carina Biotech
  • Class Antineoplastics; CAR-T cell therapies; Gene therapies; Immunotherapies
  • Mechanism of Action Immunologic cytotoxicity; T lymphocyte replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Preclinical Ovarian cancer
  • No development reported Colorectal cancer; Haematological malignancies; Solid tumours

Most Recent Events

  • 28 Aug 2026 No recent reports of development identified for preclinical development in Colorectal-cancer in Australia (Parenteral)
  • 28 Aug 2026 No recent reports of development identified for preclinical development in Haematological-malignancies in Australia (Parenteral)
  • 28 Aug 2025 No recent reports of development identified for preclinical development in Solid-tumours in Australia (Parenteral)

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