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LGR5-targeted CAR-T cell therapy - Carina Biotech

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LGR5-targeted CAR-T cell therapy - Carina Biotech

Alternative Names: LGR5 stem cell antigen - Carina Biotech

Latest Information Update: 28 Feb 2023

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At a glance

  • Originator Carina Biotech
  • Class Antineoplastics; CAR-T cell therapies; Gene therapies; Immunotherapies
  • Mechanism of Action Immunologic cytotoxicity; T lymphocyte replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Preclinical Colorectal cancer; Haematological malignancies; Ovarian cancer; Solid tumours

Most Recent Events

  • 23 Feb 2023 Carina Biotech plans to move into clinical trial in Haematological malignancies, Solid tumours, Ovarian cancer and Colorectal cancer (Late-stage disease) in 1H of 2023.
  • 06 Feb 2023 Preclinical trials in Ovarian cancer in Australia (Parenteral)
  • 06 Feb 2023 Pharmacodynamics data from preclinical trial in Ovarian cancer released by Carina Biotech

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