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JMKX 001899

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Drug Profile

JMKX 001899

Alternative Names: JMKX-001899

Latest Information Update: 26 Nov 2025

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At a glance

  • Originator Jemincare
  • Class Antineoplastics; Small molecules
  • Mechanism of Action KRAS protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Non-small cell lung cancer
  • Research Colorectal cancer

Most Recent Events

  • 21 Nov 2025 Jemincare plans a phase III trial for Non-small cell lung cancer (Late-stage disease, Metastatic disease, Second-line therapy or greater) in China (PO, once daily), in December 2025 (NCT07242274)
  • 06 Jun 2025 Phase-I clinical trials in Non-small cell lung cancer (Combination therapy, Late-stage disease, Metastatic disease) in China (PO) (NCT06946927)
  • 27 Apr 2025 Jemincare plans phase I trial in Non small cell lung cancer (Combination therapy, Metastatic disease and Late-stage disease) in China in June 2025 (PO) (NCT06946927)

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