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Actinium-225 Dotate - RayzeBio

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Drug Profile

Actinium-225 Dotate - RayzeBio

Alternative Names: 225Ac-DOTATATE; RYZ-101

Latest Information Update: 02 Jul 2024

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At a glance

  • Originator RayzeBio
  • Class Antineoplastics; Radioisotopes; Radiopharmaceuticals
  • Mechanism of Action Ionising radiation emitters
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Neuroendocrine tumours
  • Phase I Small cell lung cancer

Most Recent Events

  • 31 May 2024 Updated efficacy and adverse event data from the phase Ib/III ACTION-1 trial in Neuroendocrine tumours presented at the 60th Annual Meeting of the American Society of Clinical Oncology (ASCO-2024)
  • 13 May 2024 Jules Bordet Institute in collaboration with RayzeBio plans to initiate a phase I (AcTRESS) trial for Multiple myeloma (Late-stage disease, Second-line therapy or greater) in Belgium (IV) (NCT06411301)
  • 26 Feb 2024 RayzeBio has been acquired by Bristol-Myers Squibb

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