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GS 0321

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Drug Profile

GS 0321

Alternative Names: COM-503; GS-0321

Latest Information Update: 15 Jan 2025

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At a glance

  • Originator Compugen
  • Class Antibodies; Antineoplastics; Immunotherapies
  • Mechanism of Action Interleukin-18 binding protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase I Solid tumours

Most Recent Events

  • 07 Jan 2025 Phase-I clinical trials in Solid tumours (Late-stage disease, Metastatic disease, Recurrent, Combination therapy) in USA (IV) (NCT06759649)
  • 06 Jan 2025 Phase-I clinical trials in Solid tumours (Monotherapy, Late-stage disease, Metastatic disease, Recurrent) in USA (IV) (NCT06759649)
  • 19 Nov 2024 Compugen plans to initiate phase I clinical trial for COM 503 in Solid tumors (Late-stage disease) in the fourth quarter of 2024

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