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Tofacitinib citrate - CAGE Bio

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Drug Profile

Tofacitinib citrate - CAGE Bio

Alternative Names: 1% Tofacitinib - CAGE Bio; CGB-500; Tofacitinib citrate ointment

Latest Information Update: 11 Sep 2025

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At a glance

  • Originator CAGE Bio
  • Class 2 ring heterocyclic compounds; Amides; Anti-inflammatories; Antiasthmatics; Antineoplastics; Antipsoriatics; Antirheumatics; Eye disorder therapies; Irritable bowel syndrome therapies; Nitriles; Piperidines; Pyrimidines; Pyrroles; Skin disorder therapies; Small molecules
  • Mechanism of Action Janus kinase 1 inhibitors; Janus kinase 2 inhibitors; Janus kinase 3 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Phase II Atopic dermatitis

Most Recent Events

  • 04 Sep 2025 Efficacy and adverse events data from a phase-II clinical trials in Atopic dermatitis released by CAGE Bio
  • 18 Dec 2024 Phase-II clinical trials in Atopic dermatitis (In adolescents, In adults, In the elderly) in USA (Topical) (NCT06810050)
  • 09 Oct 2023 CAGE Bio plans a phase II trial for Atopic dermatitis (In adolescents, In adults, In the elderly) in unknown location (Topical, Ointment) (NCT06923228)

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