Drug Profile

ALG 021682

Alternative Names: ALG-021682

Latest Information Update: 29 May 2025

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At a glance

Originator Aligos Therapeutics
Class Amides; Amino sugars; Antisense oligonucleotides; Antivirals; Drug conjugates
Mechanism of Action Hepatitis B surface antigen expression inhibitors; RNA interference

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

29 May 2025 Discontinued - Preclinical for Hepatitis B in USA (SC) prior to May 2025 (Aligos Therapeutics pipeline, May 2025)
22 Jun 2022 Preclinical trials in Hepatitis B in USA (SC)
22 Jun 2022 Pharmacodynamics data from a preclinical studies in Hepatitis B presented at the The International Liver Congress 2022 (ILC-2022)

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