Drug Profile

Research programme: TROP-2 targeting therapeutics - Molecular Templates

Latest Information Update: 07 May 2025

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At a glance

Originator Molecular Templates
Class Antineoplastics; Bacterial toxins; Drug conjugates; Immunoglobulin fragments; Immunotoxins; Recombinant fusion proteins; Viral proteins
Mechanism of Action Apoptosis stimulants; Protein synthesis inhibitors; TROP2 antagonists

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

07 May 2025 Discontinued - Preclinical for Non-small cell lung cancer in USA (Parenteral) (Molecular Templates website, May 2025)
07 May 2025 Discontinued - Preclinical for Triple-negative-breast-cancer in USA (Parenteral) (Molecular Templates website, May 2025)
12 May 2022 Preclinical trials in Triple-negative beast cancer in USA (Parenteral), before May 2022

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