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IBI 343

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Drug Profile

IBI 343

Alternative Names: IBI-343

Latest Information Update: 29 Jul 2025

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At a glance

  • Originator Innovent Biologics
  • Developer Innovent Biologics; Ruijin Hospital
  • Class Alkaloids; Antineoplastics; Camptothecins; Drug conjugates; Immunoconjugates; Monoclonal antibodies
  • Mechanism of Action DNA topoisomerase I inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Adenocarcinoma
  • Phase I Solid tumours

Most Recent Events

  • 15 Jul 2025 Innovent Biologics plans a phase III G-HOPE-002 trial for Pancreatic cancer (Second-line therapy or greater, Late-stage disease, Unresectable/Inoperable, Metastatic disease) in China in July 2025 (IV, Infusion) (NCT07066098)
  • 02 Jun 2025 Phase-I/II clinical trials in Adenocarcinoma (Combination therapy, First-line therapy, Late-stage disease, Metastatic disease, Inoperable/Unresectable) in China (IV) (NCT07025889)
  • 30 May 2025 Adverse events and efficacy data from a phase I trial in Solid tumours presented at the 61st Annual Meeting of the American Society of Clinical Oncology (ASCO-2025)

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