IBI 343
Alternative Names: IBI-343Latest Information Update: 28 Nov 2025
At a glance
- Originator Innovent Biologics
- Developer Innovent Biologics; Ruijin Hospital
- Class Alkaloids; Antineoplastics; Camptothecins; Drug conjugates; Immunoconjugates; Monoclonal antibodies
- Mechanism of Action DNA topoisomerase I inhibitors
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Orphan Drug Status
No
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Phase III Adenocarcinoma; Pancreatic cancer
- Phase I Solid tumours
Most Recent Events
- 28 Nov 2025 No recent reports of development identified for phase-I development in Solid-tumours(Inoperable/Unresectable, Late-stage disease, Metastatic disease) in Australia (IV)
- 22 Oct 2025 IBI 343 licensed to Takeda worldwide outside of Greater China for the treatment of Solid tumours
- 22 Oct 2025 Innovent Biologics completes a phase I/II trial in Pancreatic cancer (Second-line therapy or greater) in China (IV)