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IBI 343

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Drug Profile

IBI 343

Alternative Names: IBI-343; TAK-921

Latest Information Update: 09 Apr 2026

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At a glance

  • Originator Innovent Biologics
  • Developer Innovent Biologics; Ruijin Hospital
  • Class Alkaloids; Antineoplastics; Camptothecins; Drug conjugates; Immunoconjugates; Monoclonal antibodies
  • Mechanism of Action DNA topoisomerase I inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Adenocarcinoma; Pancreatic cancer
  • Phase I Solid tumours
  • Clinical Phase Unknown Gastric cancer

Most Recent Events

  • 26 Mar 2026 Clinical trials in Gastric cancer (First-line therapy) (Parenteral) before March 2026
  • 26 Mar 2026 Clinical trials in Pancreatic cancer (First-line therapy) (Parenteral) before March 2026
  • 25 Mar 2026 Innovent Biologics plans a phase II trial in Adenocarcinoma (Combination therapy, Late-stage disease) in China (Parenteral) (NCT07483554)

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