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IBI 343

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Drug Profile

IBI 343

Alternative Names: IBI-343

Latest Information Update: 29 Oct 2025

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At a glance

  • Originator Innovent Biologics
  • Developer Innovent Biologics; Ruijin Hospital
  • Class Alkaloids; Antineoplastics; Camptothecins; Drug conjugates; Immunoconjugates; Monoclonal antibodies
  • Mechanism of Action DNA topoisomerase I inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Adenocarcinoma; Pancreatic cancer
  • Phase I Solid tumours

Most Recent Events

  • 22 Oct 2025 IBI 343 licensed to Takeda worldwide outside of Greater China for the treatment of Solid tumours
  • 22 Oct 2025 Innovent Biologics completes a phase I/II trial in Pancreatic cancer (Second-line therapy or greater) in China (IV)
  • 04 Aug 2025 Phase-III clinical trials in Pancreatic cancer (Second-line therapy or greater, Late-stage disease, Inoperable/Unresectable, Metastatic disease) in China (IV) (NCT07066098)

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