Either you have JavaScript disabled or your browser does not support Javascript . To work properly, this page requires JavaScript to be enabled.
How to enable JavaScript in your browser?

HRS 4642

Next Previous
Drug Profile

HRS 4642

Alternative Names: HRS-4642

Latest Information Update: 02 Sep 2025

Price :
$50 *
Note:
  • Adis is an information provider. We do not sell or distribute actual drugs.
  • Final gross price and currency may vary according to local VAT and billing address.
  • Your purchase entitles you to full access to the information contained in our drug profile at the time of purchase.
  • A link to download a PDF version of the drug profile will be included in your email receipt.

At a glance

  • Originator Jiangsu Hengrui Medicine Co.
  • Class 2 ring heterocyclic compounds; Antineoplastics; Azabicyclo compounds; Fluorinated hydrocarbons; Heterocyclic compounds with 4 or more rings; Naphthols; Oxazepines; Pyridines; Pyrimidines; Small molecules
  • Mechanism of Action KRAS protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase II Pancreatic cancer
  • Phase I/II Solid tumours

Most Recent Events

  • 02 Sep 2025 Chemical structure information added.
  • 20 Aug 2025 Jiangsu Hengrui Medicine plans a phase II trial in Adenocarcinoma (Combination therapy; Adjuvant therapy; Neoadjuvant therapy) (NCT07131514)
  • 01 May 2025 Henan Cancer Hospital plans a phase I/II trial for Solid tumours (Late-stage disease, Metastatic disease, Combination therapy, Inoperable/unresectable) in China(IV) (NCT06955390)

You need to be a logged in or subscribed to view this content

Request demo (opens in a new window)
If your organization or you do not have a subscription, try one of the following: If your organization has a subscription, there are several access options, even while working remotely:
  • Working within your organization’s network
  • with username/password or try to via your institution
  • Persisted access using your organization’s identifier stored in your user browser for 90 days
Back to top