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HRS 4642

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Drug Profile

HRS 4642

Alternative Names: HRS-4642

Latest Information Update: 08 May 2025

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At a glance

  • Originator Jiangsu Hengrui Medicine Co.
  • Class Antineoplastics
  • Mechanism of Action KRAS protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase I/II Pancreatic cancer; Solid tumours

Most Recent Events

  • 01 May 2025 Henan Cancer Hospital plans a phase I/II trial for Solid tumours (Late-stage disease, Metastatic disease, Combination therapy, Inoperable/unresectable) in China(IV) (NCT06955390)
  • 25 Apr 2025 Shanghai Zhongshan Hospital plans a phase II trial for Pancreatic Cancer in (First-line therapy, Late-stage disease, Metastatic disease, Combination therapy, Unresectable/Inoperable) in May 2025 (NCT06938282)
  • 14 Jan 2025 West China Hospital plans a phase I/II trial for Pancreatic cancer (Combination therapy, Late-stage disease, Metastatic disease, Second-line therapy or greater, Recurrent) in January 2025 (NCT06773130)

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