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VLS 1488

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Drug Profile

VLS 1488

Alternative Names: VLS-1488

Latest Information Update: 03 Jun 2025

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At a glance

  • Originator Volastra Therapeutics
  • Class Antineoplastics; Small molecules
  • Mechanism of Action KIF18A protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I/II Cancer

Most Recent Events

  • 22 May 2025 Efficacy and adverse event data from a phase I/II trial in Cancer released by Volastra Therapeutics
  • 02 Oct 2024 VLS 1488 receives Fast track status from the US FDA for Ovarian cancer (Late-stage disease, Second-line therapy or greater)
  • 31 Oct 2023 Phase-I/II clinical trials in Cancer (Second-line therapy or greater, Late-stage disease) (PO) (NCT05902988)

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