AK 130
Alternative Names: AK-130Latest Information Update: 03 Aug 2026
At a glance
- Originator Akeso Biopharma
- Class Antineoplastics; Bispecific antibodies; Immunoglobulin Fc fragments; Immunotherapies; Recombinant fusion proteins
- Mechanism of Action Immunologic cytotoxicity; TIGIT protein inhibitors; Transforming growth factor beta inhibitors
-
Orphan Drug Status
No
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Phase II Pancreatic cancer
- Phase I/II Biliary cancer; Liver cancer
- No development reported Solid tumours
Most Recent Events
- 29 May 2026 Efficacy and adverse evenet data from a phase I/II trial in Biliary cancer presented at the 62nd Annual Meeting of the American Society of Clinical Oncology 2026 (ASCO-2026)
- 28 Mar 2026 No recent reports of development identified for phase-I development in Solid-tumours(Inoperable/Unresectable, Late-stage disease, Metastatic disease) in China (IV, Infusion)
- 03 Mar 2026 Phase-I/II clinical trials in Biliary cancer (Late-stage disease, Combination therapy, Metastatic disease, Second-line therapy or greater) in China (IV) (NCT06938321)