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UCLM 802

Drug Profile

UCLM 802

Alternative Names: Anti-Mesothelin CAR-T cell therapy - UTC Therapeutics; CD40 ligand expressing MSLN-CAR T cell therapy - UTC Therapeutics; CD40 ligand targeting anti-mesothelin chimeric antigen receptor T cell therapy - UTC Therapeutics; UCLM-802

Latest Information Update: 11 May 2023

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At a glance

  • Originator UTC Therapeutics
  • Class Antineoplastics; CAR-T cell therapies; Gene therapies; Immunotherapies
  • Mechanism of Action Immunologic cytotoxicity; T lymphocyte replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Phase I/II Solid tumours

Most Recent Events

  • 27 Apr 2023 Phase-I clinical trials in Solid tumours (Second-line therapy or greater, Late-stage disease) in China (IV) (NCT05848999)
  • 24 Mar 2023 UTC Therapeutics plans a phase I trial for Solid tumours (Late staged, Relapsed or Refractory, Second-line therapy or greater) (NCT05783089)
  • 20 Mar 2023 UTC Therapeutics plans a phase I trial for Solid tumours (Late stage disease, In adults, In elderly, Second line therapy or greater) (IV) (NCT05775666)
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