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RV 01 - Radiopharm Ventures

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Drug Profile

RV 01 - Radiopharm Ventures

Alternative Names: 177Lu-BetaBart; 177lutetium BetaBart; 177Lutetium-conjugated B7-H3 radioantibody; Lu177-B7H3-mAb; Radiolabelled humanized IgG antibody - Radiopharm Venture; Radiolabelled humanized immunoglobulin G antibody - Radiopharm Ventures; RV-01 - Radiopharm Ventures

Latest Information Update: 01 Aug 2025

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At a glance

  • Originator Radiopharm Ventures
  • Developer Radiopharm Ventures; University of Texas M. D. Anderson Cancer Center
  • Class Antineoplastics; Immunoconjugates; Monoclonal antibodies; Radioisotopes; Radiopharmaceuticals
  • Mechanism of Action CD276 protein inhibitors; Ionising radiation emitters
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Solid tumours

Most Recent Events

  • 28 Jul 2025 US FDA approves IND application for RV 01 in Solid tumours
  • 28 Jul 2025 Radiopharm Ventures plans a first-in-human phase I trial for Solid tumours in USA (Parenteral), in Q4 of 2025
  • 17 Feb 2025 Radiopharm Theranostics expects to receive IND approval in Solid tumours in mid 2025 (Radiopharm Theranostics pipeline, February 2025)

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